12/26/2024 7:50:56 PM	MICRO 5 Course Outline as of Fall 2021	Changed Course
CATALOG INFORMATION
Discipline and Nbr:  MICRO 5	Title:  GENERAL MICROBIOLOGY
Full Title:  General Microbiology
Last Reviewed:8/14/2023

Units		Course Hours per Week			Nbr of Weeks	Course Hours Total
Maximum	5.00	Lecture Scheduled	3.00		17.5 max.	Lecture Scheduled	52.50
Minimum	5.00	Lab Scheduled	6.00		6 min.	Lab Scheduled	105.00
		Contact DHR	0			Contact DHR	0
		Contact Total	9.00			Contact Total	157.50
		Non-contact DHR	0			Non-contact DHR Total	0

Total Out of Class Hours:  105.00

Total Student Learning Hours: 262.50

Title 5 Category:  AA Degree Applicable
Grading:  Grade Only
Repeatability:  00 - Two Repeats if Grade was D, F, NC, or NP
Also Listed As: 
Formerly: 

Catalog Description:

Course covers the morphology, growth, metabolism, genetics, and control of microorganisms, with emphasis on bacteria and viruses. Includes principles of microbial pathogenicity, and the human immune response. Emphasis on laboratory techniques. Intended for allied health majors considering transfer to CSU or UC.

Prerequisites/Corequisites:
Course completion of ENGL 1A (OR ESL 10); AND Completion of BIO 10 or higher (V7); AND Completion of CHEM 60, CHEM 3A (OR CHEM 1A), or higher (V6)

Recommended Preparation:

Limits on Enrollment:

Schedule of Classes Information
Description:

Course covers the morphology, growth, metabolism, genetics, and control of microorganisms, with emphasis on bacteria and viruses. Includes principles of microbial pathogenicity, and the human immune response. Emphasis on laboratory techniques. Intended for allied health majors considering transfer to CSU or UC.

(Grade Only)
Prerequisites:Course completion of ENGL 1A (OR ESL 10); AND Completion of BIO 10 or higher (V7); AND Completion of CHEM 60, CHEM 3A (OR CHEM 1A), or higher (V6)
Recommended:
Limits on Enrollment:
Transfer Credit:CSU;UC.
Repeatability:00 - Two Repeats if Grade was D, F, NC, or NP

ARTICULATION, MAJOR, and CERTIFICATION INFORMATION

Associate Degree:		Effective:	Fall 1981	Inactive:
Area:	C	Natural Sciences
CSU GE:	Transfer Area			Effective:	Inactive:
	B2	Life Science		Fall 1981
	B3	Laboratory Activity
IGETC:	Transfer Area			Effective:	Inactive:
	5B	Biological Sciences		Fall 1981
	5C	Fulfills Lab Requirement
CSU Transfer:	Transferable	Effective:	Fall 1981	Inactive:
UC Transfer:	Transferable	Effective:	Fall 1981	Inactive:
C-ID:

Certificate/Major Applicable: Both Certificate and Major Applicable

COURSE CONTENT

Student Learning Outcomes:
At the conclusion of this course, the student should be able to:

1.  Integrate basic principles of microbial cell structures and processes with evolutionary and

    ecological concepts.

2.  Explain the impact of microbiology on medical, public health and environmental concerns.

3.  Demonstrate proficiency in a variety of standard laboratory techniques used for the routine

    culture, analysis and identification of microorganisms.

Objectives:

At the conclusion of this course, the student should be able to:

1. Outline the history of major microbiological discoveries and describe their contributions to

    world civilization.

2. State Koch's postulates and apply them to different types of pathogens and to new

    diseases.

3. Relate basic principles of chemistry and cell biology to structure and function of microbes.

4. Explain how the unity of basic cell processes contributes to difficulties in treating

    infectious disease.

5. Describe the principles and mechanisms of microbial genetics and coevolution and apply them

    to the problem of increasing drug resistance in microorganisms.

6. Describe viruses and their relation to cells.

7. Compare and evaluate the various mechanisms of control and prevention of microbial disease.

8. Discuss the mechanisms of pathogenicity in microbes.

9. Compare and contrast the epidemiology of community acquired and hospital acquired

    infections.

10. Describe the functions of the human immune system, its relations to disease, and how

    vaccination contributes to immunity.

11. Describe the etiology, epidemiology, treatment and prevention of a variety of important

    infectious diseases.

12. Safely and aseptically perform a variety of microbiological laboratory techniques.

13. Collect and analyze data.

Topics and Scope

I. Historical development

    A. Discovery of the microbial world and development of the microscope

    B. Spontaneous generation vs. biogenesis

    C. Koch's postulates

    D. Contribution of microbiology to biochemistry and molecular biology

    E. Contribution of microbiology to world civilization

II. Cell biology

    A. Chemistry and biochemistry review

    B. Lipids, membranes and transport

    C. DNA, RNA, protein: structure, function and flow of information

    D. ATP synthesis and cell work

    E. The eukaryotic cell: structure and function; endosymbiotic theory

    F. The prokaryotic cell: structure and function

    G. Comparison of bacteria and archaea

III. Antimicrobial agents

    A. Sterilization, disinfectants, antiseptics

    B. Antibiotics

         1. mode of action

         2. resistance mechanisms

IV. Microbial genetics

    A. Genome and phenotype

    B. Mutation, selection, adaptation

    C. Horizontal gene transfer

         1. transformation

         2. conjugation

         3. transduction

    D. Relation to virulence and antibiotic resistance

V. Viruses

    A. Definitions and historical background

    B. Interactions with cells

    C. Viral diseases of importance

VI. Ecological principles

    A. The human as ecosystem

    B. Symbiosis

    C. Impact on model of infectious disease

VII. Infectious disease

    A. Role of microbiome

    B. Mechanisms of pathogenicity

    C. Epidemiology

    D. Role of the host in disease

         1. innate resistance

         2. acquired resistance

    E. Vaccination, prevention and treatment

    F. Specific diseases of the human population

VIII. Applied microbiology

    A. Modern biotechnology

    B. Environmental microbiology

         1. wastewater treatment

         2. antibiotic isolation

         3. environmental sampling and analysis

    C. The role of hospital and public health laboratories

    D. Fermentation applications

 

Laboratory Exercises

I. Laboratory safety and sanitation

II. Laboratory Techniques

    A. Aseptic technique

    B. Bacterial culture (liquid and solid medium)

    C. Microscopy and staining techniques

    D. Preparation and sterilization techniques

    E. Analyses of bacteria in water, soil, and the community at large

    F. Antibiotic sensitivity

    G. Metabolic tests and bacterial identification

    H. Bacterial mutagenesis

    I. Transformation

    J. Polymerase chain reaction and gel electrophoresis

    K. ELISA (enzyme-linked immunosorbent assay)

Assignments:

Lecture Related Assignments:

1. Reading assignments from text, averaging one chapter per week; additional reading

    assignments averaging 1-5 pages per week

2. Research papers: 1-2, averaging 2-4 pages each

3. Quizzes: 0-15

4. Lecture exams: 3-4 (including multiple choice, completion, and essay questions)

5. Oral presentation: 1

 

Lab Related Assignments:

1. Laboratory experiments, data collection, demonstration of laboratory techniques

2. Lab exams: 2-3

Methods of Evaluation/Basis of Grade.

Writing: Assessment tools that demonstrate writing skill and/or require students to select, organize and explain ideas in writing.		Writing 4 - 15%
Research papers
Problem solving: Assessment tools, other than exams, that demonstrate competence in computational or non-computational problem solving skills.		Problem Solving 0 - 0%
None
Skill Demonstrations: All skill-based and physical demonstrations used for assessment purposes including skill performance exams.		Skill Demonstrations 1 - 15%
Laboratory experiments, data collection, demonstration of laboratory techniques
Exams: All forms of formal testing, other than skill performance exams.		Exams 70 - 90%
Quizzes, Lecture exams, Lab exams
Other: Includes any assessment tools that do not logically fit into the above categories.		Other Category 5 - 15%
Oral presentation, Attendance and participation

Representative Textbooks and Materials:

Microbiology: An Introduction. 12th ed. Tortora, Gerard and Funke, Berdell and Case, Christine. Pearson. 2016

Microbiology: A Systems Approach. 4th ed. Cowan, Marjorie. McGraw-Hill. 2015

Microbiology: A Photographic Atlas for the Laboratory. Alexander, Steven and Strete, Dennis. Pearson. 2001 (classic)

Instructor prepared lab manual

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