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I. History of Drug Development
A. Drug legislation
B. Drug testing and approval
C. Food and Drug Administration (FDA) food health claims
II. Introduction to Pharmacology
A. Receptors and mechanisms of drug action
B. Pharmacokinetics
C. Drug effects
1. Therapeutic
2. Side effects
3. Interactions
III. Administration of Pharmacologic Agents
A. Seven "Rights" for correct drug administration
B. Dosage forms and routes
C. Factors that influence drug effects
IV. Autonomic Nervous System Drugs
A. Parasympathetic Nervous System and cholinergic agents (parasympathomimetics)
B. Sympathetic Nervous System
1. Adrenergic agents (sympathomimetics)
2. Sympatholytics
V. Anti-Infectives and Drugs for the Common Cold
A. Antibiotics
1. Fighting bacterial infections
2. Antibiotic treatment and action
3. Classes of antibiotics
a. Sulfonamides
b. Penicillins
c. Cephalosporins
d. Tetracyclines
e. Macrolides
f. Quinolones
g. Streptogramins
h. Aminoglycosides
i. Miscellaneous antibiotics
B. Antivirals
C. Antiretrovirals
1. Nucleoside reverse transcriptase inhibitors (NRITs)
2. Non-nucleoside reversed transcriptase inhibitors (NNTRIs)
3. Protease inhibitors (PI's)
D. Anti-fungals
1. Topical
2. Systemic
E. Antihistamines
F. Decongestants
G. Antitussives
H. Expectorants
VI. Cardiovascular Drugs
A. Antiarrhythmics
1. Membrane stabilizing agents/sodium channel blockers (class I)
2. Beta blockers (class II)
3. Potassium channel blockers (class III)
4. Calcium channel blockers (class IV)
B. Congestive Heart Failure
1. Antiarrhythmics
2. Vasodilators
3. Angiotensin converting enxyme (ACE) inhibitors
4. Angiotensin II antagonists
C. Myocardial Infarction-Beta blockers
D. Angina Pectoris
1. Nitrates
2. Calcium channel blockers
3. Beta blockers
E. Hypertension
1. Diuretics
2. Calcium channel blockers
3. ACE inhibitors
4. Angiotensin II - receptor antagonist
5. Beta blockers
6. Central nervous system (CNS) agents
7. Peripheral acting agents
8. Vasodilators
F. Anticoagulants and Antiplatelets
1. Antiplatelet agents
2. Anticoagulant agents
3. Fibrinolytic agents
G. Hyperlipidemia
1. Hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitors
2. Fibric acid derivatives
3. Bile acid sequestrants
VII. Urinary System Drugs
A. Renal drug therapy
1. Erythropoietin therapy
2. Vitamin therapy
3. Phosphate binders
B. Urinary tract drugs
1. Antibiotics
2. Antispasmotic agents
3. Local anesthetics
C. Diuretics
1. Thiazides
2. Loop diuretics
3. Potassium sparing diuretics
4. Carbonic anhydrase inhibitors
5. Osmotic diuretics
VIII. Topicals, Ophthalmics and Otics
A. Common skin conditions
1. Acne
2. Itching
3. Psoriasis
4. Dandruff
5. Fungal infection
6. Poison ivy
7 Atopic dermatitis
8. Lice
B. Ophthalmics
1. Antibiotics
2. Corticosteroids
3. Anti-fungal
4. Antivirals
5. Agents to treat glaucoma
C. Otics
1. Analgesics
2. Antibiotics
3. Wax dissolvers
IX. Narcotic Pain Relievers and Other Nervous System Drugs
A. Anesthetics, analgesics and narcotics
1. General anesthetics
2. Pain management
a. Narcotics and opiates
b. Addiction and dependence
c. Combination drugs for managing pain
3. Migraine headaches
a. Selective 5-hydroxytryptamine receptors (5-HT) receptor agents
b. Ergot preparations
c. Antiemetic agents
d. Opioid analgesics
B. Antidepressants, antipsychotics and anti-anxiety agents
1. Antidepressants
a. Selective serotonin reuptake inhibitors (SSRI)
b. Tricyclic antidepressants
c. Monoamine Oxidase Inhibitors (MAOI)
d. Drugs used in bipolar disorders
2. Antipsychotics
3. Antianxiety agents
a. Panic disorders
b. Sleep disorders
C. Anticonvulsants and drugs to treat other nervous system disorders
1. Anti-epileptic drug therapy
2. Anti-parkinson agents
X. Respiratory Drugs
A. Asthma
B. Emphysema and chronic bronchitis
XI. Gastrointestinal Drugs
A. Peptic ulcer disease
B. Antidiarrheals/laxatives
C. Anti-inflammatory drugs
D. Anti-parasitic drugs
XII. Non-Narcotic Analgesics and Muscle Relaxants
A. Salicylates
B. Nonsteroidal anti-inflammatory drugs (NSAID)
C. Muscle relaxants
XIII. Hormones
A. Thyroid
B. Adrenal hormones
C. Corticosteroids
D. Hypoglycemic agents
E. Growth hormone
F. Female hormones
G. Contraceptives
XIV. Chemotherapy
A. Recombinant DNA agents
B. Chemotherapy agents
1. Alkylating agents
2. Antimetabolites
3. Nitrogen mustards
4. Plant alkaloids
5. Topoisomerase I inhibitors
6. Miscellaneous agents
7. Cytoprotective (rescue) agents
C. Drugs used for mucositis
XV. Vitamins and Nutritional Supplements
A. Total parenteral nutrition
B. Vitamins
C. Electrolytes
D. Natural supplements
XVI. Poisons and Antidotes
A. Antidotes
B. Supportive therapy
XVII. Code Blue Emergencies
A. Cardiac drugs
B. Respiratory drugs
C. Anti-seizure drugs
D. Diabetic drugs