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A successful student in Chemistry 12A should be able to:
1. apply bonding theory to predict and explain the bonding and three
dimensional structure of organic compounds.
2. apply simple molecular orbital theory to predict the bonding and
chemical reactivity of organic compounds.
3. use intermolecular attractive forces to predict and explain physical
properties of organic compounds.
4. apply resonance theory to organic compounds.
5. apply acid-base theory to organic compounds.
6. apply the concepts of kinetics to organic reactions.
7. apply the concepts of thermodynamics to organic reactions.
8. name simple organic compounds using the IUPAC system of nomenclature.
9. predict and draw the possible conformations of alicyclic and cyclic
organic compounds.
10. predict if a given organic structure is chiral and optically active.
11. determine the stereochemical relationship between pairs of compounds.
12. use Fischer projections to convey the stereochemical nature of a
stereocenter.
13. suggest feasible methods of synthesis of organic compounds.
14. predict the products of reactions involving organic compounds.
15. predict the influence a change in structure will have on an organic
reaction.
16. predict the influence a change in solvent will have on an organic
reaction.
17. decide if a substitution reaction is occurring by SN1 or SN2 mechanism
and predict the products.
18. decide if an elimination is occurring by E1 or E2 mechanism, and
predict the products.
19. write a logical mechanism for an organic reaction.
20. apply oxidation-reduction theory to organic compounds.
21. apply the theory of aromaticity to predict and explain the reactivity
of organic compounds.
22. explain the basic theory behind nuclear magnetic resonance
spectroscopy.
23. determine structures of simple organic compounds based on molecular
formulas and nmr spectra.
24. explain the theory behind infrared spectroscopy.
25. determine structures of simple organic compounds based on molecular
formulas and ir spectra.
26. interpret simple nmr, ir, and mass spectra.
27. operate the nuclear magnetic resonance spectrometer.
28. operate the infrared spectrophotometer.
29. perform the following laboratory techniques: crystallization, melting
point determination, extraction, simple distillation, fractional
distillation, vacuum distillation, steam distillation, boiling point
determination and chromatographic separations.
30. explain the theory behind the techniques of crystallization, melting
point determination, extraction, simple distillation, fractional
distillation, vacuum distillation, steam distillation, boiling point
determination and chromatographic separations.
31. operate a gas chromatograph, and gas chromatograph equipped with mass
spectrometer.
32. analyze a gas chromatogram.
33. keep a laboratory notebook according to the research standards.
34. effectively communicate observations and subsequent conclusions by
means of written laboratory reports.
35. utilize reference books and/or online databases for the construction
of laboratory reports.
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LECTURE MATERIAL
1. General chemical concepts of bonding and structure.
2. Structure of organic compounds.
3. Acid-base chemistry.
4. Alkanes and cycloalkanes.
5. Stereochemistry.
6. Nucleophilic substitution and elimination reactions.
7. Alkenes and alkynes.
8. Alcohols.
9. Dienes.
10. Radical reactions.
11. Aromaticity.
12. Spectroscopy: NMR and IR. .
LABORATORY MATERIAL
1. Nuclear magnetic resonance spectroscopy.
2. Infrared spectroscopy.
3. Crystallization.
4. Melting point determinations.
5. Simple distillation.
6. Fractional distillation.
7. Vacuum distillation.
8. Steam distillation.
9. Gas chromatography/mass spectrometry.
10. Thin layer and column chromatography.
11. Polarimetry.
12. Isolation of organic compounds.
13. Synthesis of organic compounds.
14. Structure determination.
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LECTURE:
ORGANIC CHEMISTRY, M. Jones Jr., N.W. Norton and Company, 1997
ORGANIC CHEMISTRY, 6th Edtion, Solomons, Wiley, 1996.
INTRODUCTION TO ORGANIC CHEMISTRY, 4th Edition, Streitweiser,
Heathcock, and Kosower, MacMillan, 1992.
ORGANIC CHEMISTRY, 4th Edition, Wade, Prentice Hall, 1999.
LABORATORY:
INTRODUCTIN TO ORGANIC LABORATORY TECHNIQUES: A MICROSCALE APPROACH, 3rd
Edition, Pavia, Lampman, Kriz, and Engel, Saunders, 1999.
EXPERIMENTAL ORGANIC CHEMISTRY: A MINISCALE APPROACH, Roberts, Gilbert,
and Martin, Saunders, 1994.