SRJC Course Outlines

12/10/2023 5:42:27 AMBIO 3 Course Outline as of Fall 2000

Changed Course

Discipline and Nbr:  BIO 3Title:  FUNDAMENTALS OF BIO  
Full Title:  Fundamentals of Biology (Cell and Molecular)
Last Reviewed:8/14/2023

UnitsCourse Hours per Week Nbr of WeeksCourse Hours Total
Maximum5.00Lecture Scheduled4.0017.5 max.Lecture Scheduled70.00
Minimum5.00Lab Scheduled3.006 min.Lab Scheduled52.50
 Contact DHR0 Contact DHR0
 Contact Total7.00 Contact Total122.50
 Non-contact DHR0 Non-contact DHR Total0

 Total Out of Class Hours:  140.00Total Student Learning Hours: 262.50 

Title 5 Category:  AA Degree Applicable
Grading:  Grade Only
Repeatability:  00 - Two Repeats if Grade was D, F, NC, or NP
Also Listed As: 
Formerly:  BIO 1.3

Catalog Description:
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Intended for major in biological sciences, pre-medical or related pre-professional programs. Cell structure and function, biochemistry, metabolism, molecular genetics, cell differentiation and development and their application to the study of selected cell types. (Formerly Biology 1.3)

Chem 1A or equivalent with grade of "C" or better.

Recommended Preparation:
Course Eligibility for ENGL 1A

Limits on Enrollment:

Schedule of Classes Information
Description: Untitled document
Intended for majors in biological sciences, pre-medical or related pre- professional programs. Cell structure & function , biochem, metabolism, molecular genetics, cell differentiation & development & their application to the study of selected cell types.
(Grade Only)

Prerequisites:Chem 1A or equivalent with grade of "C" or better.
Recommended:Course Eligibility for ENGL 1A
Limits on Enrollment:
Transfer Credit:CSU;UC.
Repeatability:00 - Two Repeats if Grade was D, F, NC, or NP


Associate Degree:Effective:Fall 1981
Natural Sciences
CSU GE:Transfer Area Effective:Inactive:
 B2Life ScienceFall 1981
 B3Laboratory Activity  
IGETC:Transfer Area Effective:Inactive:
 5BBiological SciencesFall 1981
 5CFulfills Lab Requirement  
CSU Transfer:TransferableEffective:Fall 1981Inactive:
UC Transfer:TransferableEffective:Fall 1981Inactive:
 CID Descriptor: BIOL 190 Cell and Molecular Biology SRJC Equivalent Course(s): BIO2.1

Certificate/Major Applicable: Not Certificate/Major Applicable


Outcomes and Objectives:
At the conclusion of this course, the student should be able to:
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The students completing Biology 1.3 will be able to:
1.  Describe the bonding, 3-D structure and reactivity of the primordial
molecules and build models of these molecules.
2.  Explain the role of the primordial molecules in the structure and
function of macro-molecules.
3.  Describe the relations of structure and function in DNA, RNA, and
4.  Describe the role of water and hydrophobic forces in the formation of
5.  Describe the organization of procaryotes and eucaryotes and explain
it's evolutionary significance.
6.  Isolate and grow cells in pure culture. Construct a growth curve.
7.   Explain the historical development of molecular genetics, describe
the experiments supporting the identity of DNA as genetic material
and those demonstrating it's heterocatalytic and regulating functions.
8.  Describe DNA replication and explain it's dependence on 3-D
9.  Distinguish mutation from re-combination and describe their role in
10. Describe procaryotic recombination systems and explain their role
in biotechnology.
11. Describe protein synthesis and explain the role of RNA.
12. Explain how changes in DNA, RNA, and Protein sequences are used to
measure evolution.
13. Define virus, explain it's interactions with the cell and relate
to other mobile genetic elements.
14. Isolate, cut, and splice DNA molecules. Transfer DNA and select
for re-combinats. Purify DNA using chromatography and
15. Titrate virus.
16. Explain the specificity of enzyme catalysis and relate to
activation energy.
17. Explain cell regulation based on the operon model and allosteric
18. Differentiate between procaryotic and eucaryotic regulation.

Topics and Scope
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1.  Basic Chemistry of Life.
     A. origin and definition of life
     B. atoms and molecules
     C. water and the carbon atom
     D. chemical reactions and enzymes
2.  Biochemistry of the Cell.
     A. sugars and polymers of sugars
     B. lipids
     C. proteins
     D. nucleic acids
3.  Structural Characteristics of Viruses and Cells.
     A. cell theory
     B. cell sizes and shapes
     C. structure of viruses and prokaryotic cells
     D. structure of eukaryotic cells
4.  The Cell Membrane.
     A. membrane structure and function
          1. diffusion and osmosis
          2. active transport
          3. the fluid mosaic model
          4. recognition
     B. the nucleus and cell division
5.  Molecular Genetics.
     A. Mendel review and connect classical to modern genetics
     B. genes and chromosones
     C. DNA: structure, replication, repair and protein coding
     D. RNA and it's specialized roles
          1. post transcriptional modification
     E. protein synthesis
          1. regulation (regulatory genes - the operon)
     F  diversity
          1. mutation
          2. recombination
             a. virus and retrovirus
          3. procaryotic mechanisms
          4. lymphocyte genetics
     G.  biotechnology
          1. vectors, enzymes, recombinants
             a. isolation, purification, and transfer of DNA and
                selection of recombinants
     H.  molecular evolution
           1. random chemistry and biological clocks
           2. phenotypic effects
     I.  new ideas in genetecs  (split genes, chromosomal protein,
         junk DNA, catalytic RNA)
6.    Proteins.
     A.  the folding problem
     B.  structural proteins
     C.  enzymes and catalysis
           1. mechanisms
     D.  allosteric regulation
     E.  antibodies
           1. domains and modular construction
7.   Cell Specialization.
     A.  developmental biology
     B.  the immune response

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1.  Textbook - reading one to two chapters per week.
2.  Outside reading - ten to twelve pages per week.
3.  Term paper - approximately ten pages.
4.  Significant preparation for upcoming lab assignments (ten to twenty
pages per week). Completion of two lab reports (five to ten pages and
fifteen to twenty pages).

Methods of Evaluation/Basis of Grade.
Writing: Assessment tools that demonstrate writing skill and/or require students to select, organize and explain ideas in writing.Writing
50 - 80%
Essay exams, Term papers, UP TO 50% ESSAY EXAMS, UP TO 10% TERM PAPER
Problem solving: Assessment tools, other than exams, that demonstrate competence in computational or non-computational problem solving skills.Problem Solving
5 - 10%
Skill Demonstrations: All skill-based and physical demonstrations used for assessment purposes including skill performance exams.Skill Demonstrations
5 - 10%
Class performances
Exams: All forms of formal testing, other than skill performance exams.Exams
10 - 40%
Multiple choice, True/false, Matching items, Completion, OBJECTIVE ON FINAL UP TO 50%
Other: Includes any assessment tools that do not logically fit into the above categories.Other Category
0 - 0%

Representative Textbooks and Materials:
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BIOLOGY: Campbell, Neil A.; 3rd Edition, 1995
MOLECULAR BIOLOGY OF THE CELL by Bruce Alberts; 3rd edition, 1994, et al.

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