12/22/2024 3:43:00 AM	BIO 20 Course Outline as of Spring 2005	Changed Course
CATALOG INFORMATION
Discipline and Nbr:  BIO 20	Title:  HUMAN GENETICS
Full Title:  Human Genetics
Last Reviewed:9/23/2024

Units		Course Hours per Week			Nbr of Weeks	Course Hours Total
Maximum	3.00	Lecture Scheduled	3.00		17.5 max.	Lecture Scheduled	52.50
Minimum	3.00	Lab Scheduled	0		17.5 min.	Lab Scheduled	0
		Contact DHR	0			Contact DHR	0
		Contact Total	3.00			Contact Total	52.50
		Non-contact DHR	0			Non-contact DHR Total	0

Total Out of Class Hours:  105.00

Total Student Learning Hours: 157.50

Title 5 Category:  AA Degree Applicable
Grading:  Grade or P/NP
Repeatability:  00 - Two Repeats if Grade was D, F, NC, or NP
Also Listed As: 
Formerly: 

Catalog Description:

Mechanisms of heredity with specific reference to humans. Course includes new genetic technologies, and their ethical and societal consequences.

Prerequisites/Corequisites:

Recommended Preparation:
Eligibility for ENGL 100 or ESL 100

Limits on Enrollment:

Schedule of Classes Information
Description:

Mechanisms of heredity with specific reference to humans. Course includes new genetic technologies, and their ethical and societal consequences.

(Grade or P/NP)
Prerequisites:
Recommended:Eligibility for ENGL 100 or ESL 100
Limits on Enrollment:
Transfer Credit:CSU;UC.
Repeatability:00 - Two Repeats if Grade was D, F, NC, or NP

ARTICULATION, MAJOR, and CERTIFICATION INFORMATION

Associate Degree:		Effective:	Fall 1981	Inactive:	Summer 2011
Area:	C C	Natural Sciences Natural Sciences
CSU GE:	Transfer Area			Effective:	Inactive:
	B2	Life Science		Fall 2020
	B2	Life Science		Fall 1981	Summer 2011
IGETC:	Transfer Area			Effective:	Inactive:
	5B	Biological Sciences		Fall 2020
	5B	Biological Sciences		Fall 1981	Summer 2011
CSU Transfer:	Transferable	Effective:	Fall 1981	Inactive:	Summer 2011
UC Transfer:	Transferable	Effective:	Fall 1981	Inactive:	Summer 2011
C-ID:

Certificate/Major Applicable: Not Certificate/Major Applicable

COURSE CONTENT

Outcomes and Objectives:
At the conclusion of this course, the student should be able to:

Upon completion of the course, student will be able to:

1.  Identify the structure and functions of major biological molecules.

2.  Describe cellular organization and structure.

3.  Explain the role and chemistry of chromosomes, DNA, and RNA in

   cell function and information transfer.

4.  Compare and contrast cellular replication/duplication by means of

   meiosis vs. mitosis.

5.  Differentiate sperm and oocyte formation, describe fertilization and

   human development.

6.  Differentiate genotype and phenotype genetic expression.

7.  Explain basic Mendelian inheritance and patterns of Mendelian

   pedigrees.

8.  Describe extensions and exceptions to Mendel's laws, including the

   inheritance of complex traits.

9.  Explain mutation and its relationship to genetic disease.

10. Describe recent advances in genetics such as recombinant DNA, genetic

   engineering, and the human genome project and how they are applied in

   gene therapy, genetic testing, and the creation of genetically-

   modified organisms.

11. Evaluate how new technologies impact us at the individual, family and

   socio-cultural levels.

12. Examine the history of eugenics and its current manifestations.

Topics and Scope

1.  History of genetics "Mendel's laws"

2.  Cell structure

3.  Cell function as applied to genetics

4.  Information machinery of the cell

     a. the nucleus: structure, DNA, RNA

     b. the chromosomes: structure and function

     c. protein synthesis

5.  Communication between generations

     a. mitosis

     b. meiosis

     c. formation of sperm and oocytes

     d. development of zygote: differentiation

6.  Genotype vs. Phenotype

     a. loci vs. alleles

     b. biochemical basis of phenotype

7.  Sex chromosomes

     a. sex determination

     b. human sex ratios

     c. sex linkage

     d. abnormalities of sex chromosomes

8.  Gene Interaction

     a. genetic ratios

     b. crossing over

     c. linkage

     d. dominance relationships

     e. cytoplasmic inheritance

     f. epistasis

     g. penetrance and expressivity

9.  Polygenic systems

     a. the normal distribution

     b. role of environment

10. Mutation - genetic disease

     a. types

     b. rates

     c. macro vs. micro mutation

     d. causes

     e. human examples - case studies

11. Recent developments in genetics

     a. recombinant DNA

     b. genetic engineering

     c. the human genome project

     d. gene therapy

     e. preimplantation genetic diagnosis

     f. genetic testing

     g. genetically-modified organisms

     h. stem cells

     i. assisted reproduction techniques

12. Eugenics

     a. historical perspective

     b. reproductive choice and the new eugenics

Assignments:

1. Reading in textbooks, scientific journals, and articles from newspaper,

  magazines and the internet; approximately 15-35 pages/week.

2. Homework: may include problem sets, and written descriptions or

  discussions of lecture topics in short essay format.

3. Oral reports: students will work in small groups, research an approved

  topic, and present a 10-15 minute report to the class.

4. Formal assessment: midterm and final examinations, including objective

  type questions, genetics problems, and essay questions.

Methods of Evaluation/Basis of Grade.

Writing: Assessment tools that demonstrate writing skill and/or require students to select, organize and explain ideas in writing.		Writing 10 - 20%
Written homework
Problem solving: Assessment tools, other than exams, that demonstrate competence in computational or non-computational problem solving skills.		Problem Solving 10 - 20%
Homework problems
Skill Demonstrations: All skill-based and physical demonstrations used for assessment purposes including skill performance exams.		Skill Demonstrations 10 - 20%
In class oral reports
Exams: All forms of formal testing, other than skill performance exams.		Exams 40 - 70%
Multiple choice, True/false, Matching items, Completion, Objective style questions (problems, essays)
Other: Includes any assessment tools that do not logically fit into the above categories.		Other Category 0 - 10%
Attendance, participation in group work

Representative Textbooks and Materials:

HUMAN GENETICS: CONCEPTS AND APPLICATIONS, by R. Lewis, McGraw-Hill

Publishers, Fourth Edition, 2001

Recommended Books:

CARTOON GUIDE TO GENETICS: (updated edition), by L. Gonick and M. Wheelis,

1991, Harper Collins

GENOME: by Matt Ridley, 1999, Harper Collins

HUMAN HEREDITY: PRINCIPLES & ISSUES, by Michael R. Cummings, 6th Edition,

Thomson Learning, 2003.

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