4/16/2024 12:30:00 AM	BIO 2.1 Course Outline as of Spring 2013	Changed Course
CATALOG INFORMATION
Discipline and Nbr:  BIO 2.1	Title:  FUND BIO: CELL
Full Title:  Fundamentals of Biology (Cell and Molecular)
Last Reviewed:8/14/2023

Units		Course Hours per Week			Nbr of Weeks	Course Hours Total
Maximum	5.00	Lecture Scheduled	3.00		17.5 max.	Lecture Scheduled	52.50
Minimum	5.00	Lab Scheduled	6.00		8 min.	Lab Scheduled	105.00
		Contact DHR	0			Contact DHR	0
		Contact Total	9.00			Contact Total	157.50
		Non-contact DHR	0			Non-contact DHR Total	0

Total Out of Class Hours:  105.00

Total Student Learning Hours: 262.50

Title 5 Category:  AA Degree Applicable
Grading:  Grade Only
Repeatability:  00 - Two Repeats if Grade was D, F, NC, or NP
Also Listed As: 
Formerly:  BIO 3

Catalog Description:

Cell structure and function, origin, evolution and diversity of cells, biochemistry, metabolism, Mendelian genetics, molecular genetics, cell regulation, cell differentiation and evolutionary  development. Intended for students majoring in biological sciences, pre-medical or related pre-professional programs. (Formerly BIO 1.3, BIO 3)

Prerequisites/Corequisites:
Course Completion of CHEM 1A and Course Completion of BIO 10 and Course Completion of ENGL 1A OR Course Completion of CHEM 4A and Course Completion of BIO 10 and Course Completion of ENGL 1A

Recommended Preparation:

Limits on Enrollment:

Schedule of Classes Information
Description:

Cell structure and function, origin, evolution and diversity of cells, biochemistry, metabolism, Mendelian genetics, molecular genetics, cell regulation, cell differentiation and evolutionary  development. Intended for students majoring in biological sciences, pre-medical or related pre-professional programs. (Formerly BIO 1.3, BIO 3)

(Grade Only)
Prerequisites:Course Completion of CHEM 1A and Course Completion of BIO 10 and Course Completion of ENGL 1A OR Course Completion of CHEM 4A and Course Completion of BIO 10 and Course Completion of ENGL 1A
Recommended:
Limits on Enrollment:
Transfer Credit:CSU;UC.
Repeatability:00 - Two Repeats if Grade was D, F, NC, or NP

ARTICULATION, MAJOR, and CERTIFICATION INFORMATION

Associate Degree:		Effective:	Fall 1981	Inactive:
Area:	C	Natural Sciences
CSU GE:	Transfer Area			Effective:	Inactive:
	B2	Life Science		Fall 1981
	B3	Laboratory Activity
IGETC:	Transfer Area			Effective:	Inactive:
	5B	Biological Sciences		Fall 1981
	5C	Fulfills Lab Requirement
CSU Transfer:	Transferable	Effective:	Fall 1981	Inactive:
UC Transfer:	Transferable	Effective:	Fall 1981	Inactive:
C-ID:
CID Descriptor: BIOL 190	Cell and Molecular Biology	SRJC Equivalent Course(s): BIO2.1

Certificate/Major Applicable: Major Applicable Course

COURSE CONTENT

Outcomes and Objectives:
At the conclusion of this course, the student should be able to:

Upon completion of the course, students will be able to:

1. Use the scientific method to develop and test hypotheses.

2. Explain current hypotheses on the diversity,  origins and evolution of cellular

life.

3. Differentiate the structure and function of prokaryotic and eukaryotic

cells.

4. Relate the properties of biochemical macromolecules to the structure

and function of cell membranes and organelles.

5. Compare and contrast the mechanisms of cell respiration and

photosynthesis.

6. Describe the transmission of genetic information through sexual and

asexual reproduction and the inheritance of traits via Mendelian genetics.

7. Explain the molecular flow of information from DNA to RNA to protein.

8. Explain cell regulation based both on control of gene expression and on signal reception and transduction.

9. Explain how cells become differentiated during the processes of embryogenesis and development, and how the mechanisms of cellular differentiation contribute to evolutionary change.

10. Use the microscope proficiently and perform a variety of standard

laboratory techniques used for the study of cells, DNA and proteins.  

11. Analyze and present student-generated data using formal scientific paper format.

Topics and Scope

I. Introduction to biology

       A. Characteristics of life

       B. Biological levels of organization

       C. Disciplines of biology

       D. Scientific method

       E. Evolution and biological thought

       F. Cell theory and origins of cells

II. The chemistry of life

       A. Atoms and molecules

       B. Water and carbon

       C. Biochemistry

       D. Chemical reactions

III. Cell structure and function

       A. Cell theory

       B. Evolution, classification and diversity of cells

       C. Archaea vs Bacteria vs Eukarya

       D. Cytoskeleton and organelles

       E. Cell membranes and transport

       F. Bioenergetics and enzymes

IV. Energy flow in cells

       A. Cell respiration reactions

       B. Photosynthesis reactions

V. Information flow in cells

       A. Cell reproduction: mitosis and meiosis

       B. Inheritance: genes and chromosomes

       C. Mendelian genetics

          1. Monohybrid crosses

          2. Dihybrid crosses

          3. Probability theory

          4. Sex-linkage, epistasis, multi-gene traits and pleiotropy

          5. Chi-squared analysis of genetic data

       D. Structure, replication, mutation and repair of DNA

       E. Transcription, RNA processing and translation

       F. Genetic regulation: epigenetics, transcriptional and post-transcriptional regulation, signal transduction pathways and allosteric proteins

VI. Cell differentiation and evolutionary development

       A. Gamete formation and fertilization

       B. Embryonic development and stem cells

       C. Enhancers and specific transcription factors

       D. Homeotic genes and morphogens

       E. Generation of diversity in animals

VII. Laboratory exercises

       A. Molecular model building

       B. Microscopy, cell structure, diversity and adaptation

       C. Statistical analysis of data: chi square and probability theory

       D. Enzyme activity

       E.  Drosophila monohybrid and dihybrid crosses

       F. Chromatography of Drosophila eye color pigments

       G.  Bacterial transformation

       H.  Plasmid DNA extraction and restriction enzyme disgestion

       I. Gel electrophoresis of DNA

       J. Polymerase chain reaction

       K. Performance of student-designed original experiments

Assignments:

1. Weekly reading in text, 30-60 pages per week.

2. Lab reports: may include calculation, graphing, data analysis, and explanation of ideas in writing 3 reports per semester.

3. Original group research project, written as a scientific paper and presented. May include calculation, graphing and data analysis as well as explanation of ideas.

4. Formal assessment: 4 midterm exams, including objective and essay questions, 1 lab practical

examination,  and 6-9 quizzes may be required.

Methods of Evaluation/Basis of Grade.

Writing: Assessment tools that demonstrate writing skill and/or require students to select, organize and explain ideas in writing.		Writing 20 - 30%
Research project, research paper
Problem solving: Assessment tools, other than exams, that demonstrate competence in computational or non-computational problem solving skills.		Problem Solving 10 - 15%
Lab reports
Skill Demonstrations: All skill-based and physical demonstrations used for assessment purposes including skill performance exams.		Skill Demonstrations 0 - 0%
None
Exams: All forms of formal testing, other than skill performance exams.		Exams 60 - 70%
Multiple choice, completion, essay questions, lab exams, quizzes
Other: Includes any assessment tools that do not logically fit into the above categories.		Other Category 0 - 5%
Group presentation

Representative Textbooks and Materials:

Biology, 9th edition, Campbell and Reece; Pearson Benjamin Cummings, 2011

World of the Cell, 8th edition, Wayne M. Becker, Lewis J. Kleinsmith,

Jeff Hardin; Pearson Benjamin Cummings, 2011

Essential Cell Biology, 3rd edition, Bruce Alberts, Dennis Bray, Karen Hopkin, Alexander Johnson, Garland Science, 2010

Instructor prepared lab manual

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